An entire fantasy, anime, or sci fi comic filled with a hero team of Mary Sues.

I wonder how you would work a team filled entirely with Mary Sues given as a Mary Sue is generally the single most important focus of attention and inconceivably better than every other character etc. etc.

Actually now that I think of it, some decent writer could probably wring a pretty okaycomic out of a whole castful of would-be Mary Sues all competing to be the Mary Suesiest.

Make some sort of reality show out of it.

Dominic Deegan has already been created.

Also,

SUPER KAWAII OMG DESU?!!?!

No, but really, that's awful, and you should feel bad.

It's so nice having never read Dominic Deegan, because whenever someone mentions that they hate it and why, I'm blissfully unaware.

My submission: Any sprite-based webcomic using Cho Anki sprites.

Damn! Guess I'll have to find somewhere else to plug Holy Protein Theater.

I had an idea for a comic the other day wherein it's the 2012 election, and the two party system has been taken to the most ridiculous extreme:

Panel 1: Man watching TV. TV: "Vote now! Text Obama or McCain to 58008!"
Panel 2: Man pulls out cell phone and texts.
Panel 3: View changes to over his shoulder, looking at screen which reads "Thank you, all other decisions will be automatically selected to fit your probable political views." Man: "Hey!"