Edit: Got distracted and ninja'd. Whatever.
Well, except the entire crew was made up entirely of aliens, and most of the game went about showing how much humans were exactly the same.
Then you have Williams, whom has never really interacted with aliens except for (probably) Terra Firma holovids being anti-alien, while in the meantime you have Kaiden whom was beaten, broken, watched his friend have her arm broken, and killed a Turian in self defense, coming away from the whole thing saying aliens are just as 'human' as anyone else.
Also: In the First Contact War more Turian lives were lost than human lives. The second fleet was able to decimate what Turian forces were sent to attack humanity, and while a full blown war at that time would have probably gone in their favor, one during the time frame of the actual games probably wouldn't given that the humans have one the strongest militaries in the ME universe (probably owing to the First Contact War).
So, no, paranoia of them 'wiping out humanity without blinking an eye' isn't exactly warranted, nor is any misconception about superior alien technology.
Also, any time speaking with any other race would show that any assumptions anyone was making about the humans not being given a position of power of authority is blatantly false, as humans gained more political power faster than any other race, the council founders aside.
And Mass Effect takes place two full generations after the Alliance was inducted into the council.
So it's not even a 'just woke up and they were there', thing. Ashley would have been raised knowing that aliens exist and all about the politics and what not surrounding them.
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