Talking about Mass Effect 3 With Spoilers

[Bells]

Well, the cast of ME2 is pretty symbolic to represent all the major factions/races in the Universe... for instance, you have Jacob and Miranda. Now, Jacob is your "Former Alliance" soldier, while Miranda is your Cerberus loyal. These two mirror pretty well where you are going to place your Loyalty regarding Earth and Humanity.

Also, Both kinda start the game Stiff and distant, but i noticed, the more Paragon i got, and spcially after Jacob's Loyalty mission, the guy relaxed and seemed like a pretty decent fellow. Miranda was going down that road too.. untill i choose Jack's side and she shut me off...

Having Samara or Morinth in your game also has Weight to your game. Having Samara might mean that you will have the Justicars on your Side... or maybe, if they come to earth, Killing-prone as they all are, your relationship with Samara might affect their views with Shepard.